Abstract Rationale: Despite the critical role of choice processes in substance use disorders, the neurobehavioral mechanisms guiding human decisions about…
Abstract Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid…
Abstract Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate its treatment. AEF0117, the first of…
Abstract Cannabis is increasingly used by individuals with mental health diagnoses and often purported to treat anxiety and various other…
Abstract Most drugs of abuse lead to a general blunting of dopamine release in the chronic phase of dependence, which…
Authors: Daniele Piomelli, Margaret Haney, Alan J. Budney, Pier Vincenzo Piazza Affiliations: Department of Anatomy and Neurobiology, School of Medicine,…