Studies of Cannabinoid-Based Products in ClinicalTrials.gov: A Scoping Review
Abstract Background and Objectives: There is increased interest in using cannabinoid-based products for therapeutic purposes. Because of unique regulatory challenges…
Margaret Haney
Value signals guiding choices for cannabis versus non-drug rewards in people who use cannabis near-daily
Abstract Rationale: Despite the critical role of choice processes in substance use disorders, the neurobehavioral mechanisms guiding human decisions about…
The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses
Abstract Cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid…
Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials
Abstract Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate its treatment. AEF0117, the first of…
Human Laboratory Models of Cannabis Use: Applications for Clinical and Translational Psychiatry Research
Abstract Cannabis is increasingly used by individuals with mental health diagnoses and often purported to treat anxiety and various other…
Deficits in striatal dopamine release in cannabis dependence
Abstract Most drugs of abuse lead to a general blunting of dopamine release in the chronic phase of dependence, which…
Legal or Illegal, Cannabis Is Still Addictive
Authors: Daniele Piomelli, Margaret Haney, Alan J. Budney, Pier Vincenzo Piazza Affiliations: Department of Anatomy and Neurobiology, School of Medicine,…