Maren Kleine-Brueggeney

May 13, 2025

Effects of intravenous d9-THC on pupillary reaction and pupil size: a prospective, placebo-controlled trial in healthy volunteers not regularly consuming cannabis

Abstract Introduction: This prospective, single-blind, placebo-controlled trial examined the effects of intravenous delta-9-tetrahydrocannabinol (d9-THC) on the pupillary light reflex and…

April 5, 2025

Pharmacokinetic/Pharmacodynamic Modeling of the Acute Heart Rate Effects of Delta-9 Tetrahydrocannabinol and Its Major Metabolites After Intravenous Injection in Healthy Volunteers

Abstract Background and Objectives: Cannabis consumption is increasing in both the recreational and medical settings. Tetrahydrocannabinol (THC) is known to…

December 18, 2024

Quantification and time course of subjective psychotropic and somatic effects of tetrahydrocannabinol – a prospective, single-blind, placebo-controlled exploratory trial in healthy volunteers

Abstract Background: Cannabis is increasingly used and debates about the legalisation of the recreational use of cannabis are ongoing. In…