Functional Adaptation in the Brain Habenulo–Mesencephalic Pathway During Cannabinoid Withdrawal
Abstract The mesolimbic reward system originating from dopamine neurons in the ventral tegmental area (VTA) of the midbrain shows a…
Marco Pistis
Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates
Abstract Background and Purpose: Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH‐018, have been marketed as marijuana surrogates since…
Δ9-Tetrahydrocannabinol During Adolescence Attenuates Disruption of Dopamine Function Induced in Rats by Maternal Immune Activation
Abstract The combination of prenatal, such as maternal infections, and postnatal environmental insults (e.g., adolescent drug abuse) increases risks for…
Cell-specific STORM superresolution imaging reveals nanoscale organization of cannabinoid signaling
Abstract A major challenge in neuroscience is to determine the nanoscale position and quantity of signaling molecules in a cell-type-,…
Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid
Abstract In the reward circuitry of the brain, alpha-7-nicotinic acetylcholine receptors (α7nAChRs) modulate effects of delta-9-tetrahydrocannabinol (THC), marijuana’s main psychoactive…