Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold
Abstract A growing body of evidence underlines the crucial role of GPR55 in physiological and pathological conditions. In fact, GPR55…
Marco Macchia
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis
Abstract Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in…
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides
Abstract We have recently identified 1,8-naphthyridin-2(1H)-one-3-carboxamide as a new scaffold very suitable for the development of new CB2 receptor potent…