Abstract Background: Today more and more people search the web for health-related information, risking to come across misinformation and biased…
Abstract To date, no psychotropic medication has shown to effectively halt progression to psychosis among individuals at Clinical High-Risk for…
Abstract Background: The diathesis-stress paradigm and the cannabinoid-hypothesis have been proposed as possible pathophysiological models of schizophrenia. However, they have…
Abstract Introduction: The endocannabinoid (eCB) system disruption has been suggested to underpin the development of psychosis, fueling the search for…
Abstract Evidence indicates shared physiopathological mechanisms between autism and psychosis. In this regard, the endocannabinoid system has been suggested to…
Abstract Antiseizure medications are the cornerstone pharmacotherapy for epilepsy. They are not devoid of side effects. In search for better-tolerated…
Abstract High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally,…
Abstract Autism spectrum disorder (ASD) pathophysiology is not completely understood; however, altered inflammatory response and glutamate signaling have been reported,…
Abstract Cannabis use during the critical neurodevelopmental period of adolescence, may lead to brain structural, functional, and histological alterations that…
Abstract Research evidence suggests a dose–response relationship for the association between cannabis use and risk of psychosis. Such relationship seems…