Tetrahydrocannabivarin is Not Tetrahydrocannabinol
Abstract Tetrahydrocannabivarin (THCV) is a phytocannabinoid that is becoming popular across the North American cannabis market. THCV has been reported…
Marcel O. Bonn-Miller
Pharmacokinetics of Oral Cannabinoid Δ8-Tetrahydrocannabivarin and Its Main Metabolites in Healthy Participants
Abstract Background: Tetrahydrocannabivarin (THCV) is a phytocannabinoid commonly found in cannabis with potential pharmacological properties; however, its post-acute pharmacokinetics (PK)…
CBD Versus CBDP: Comparing In Vitro Receptor-Binding Activities
Abstract Phytocannabinoids with seven-carbon alkyl chains (phorols) have gained a lot of attention, as they are commonly believed to be…
Cannabielsoin (CBE), a CBD Oxidation Product, Is a Biased CB1 Agonist
Abstract Cannabielsoin (CBE) is primarily recognized as an oxidation byproduct of cannabidiol (CBD) and a minor mammalian metabolite of CBD.…
Using In Silico Molecular Docking to Explain Differences in Receptor Binding Behavior of HHC and THCV Isomers: Revealing New Binding Modes
Abstract Even slight structural differences between phytocannabinoid isomers are usually enough to cause a change in their biological properties. In…
Serum Markers of Bone Turnover Following Controlled Administration of Two Medical Cannabis Products in Healthy Adults
Abstract Introduction: Cannabidiol (CBD) has been shown to maintain bone integrity in pre-clinical models, but little is known about the…
A randomized, double-blind, placebo-controlled, repeated-dose pilot study of the safety, tolerability, and preliminary effects of a cannabidiol (CBD)- and cannabigerol (CBG)-based beverage powder to support recovery from delayed onset muscle soreness (DOMS)
Abstract Background: Cannabinoid-containing products are marketed to athletes as promoting recovery, in spite of a lack of data on their…
Cannabinoid Content and Label Accuracy of Hemp-Derived Topical Products Available Online and at National Retail Stores
Abstract Question: Are hemp-derived topical cannabinoid products available online and at national retailers accurately labeled for cannabidiol (CBD) and Δ9-tetrahydrocannabinol…
Adjunctive Transdermal Cannabidiol for Adults With Focal Epilepsy
Abstract This randomized clinical trial evaluates the use of transdermal cannabidiol vs placebo for adults with drug-resistant focal epilepsy. Authors:…
Effect of Cannabidiol on the Long-Term Toxicity and Lifespan in the Preclinical Model Caenorhabditis elegans
Abstract Introduction: Despite widespread use of cannabidiol (CBD), no lifelong toxicity study has been published to date. Caenorhabditis elegans is…