Abstract Background: Phytocannabinoids naturally occur in the cannabis plant (Cannabis sativa), and Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) predominate. There is…
Abstract Background: The lack of an agreed international minimum approach to measuring cannabis use hinders the integration of multidisciplinary evidence…
Abstract Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during…
Abstract Premise: How genetic variation within a species affects phytochemical composition is a fundamental question in botany. The ratio of…
Abstract Cannabidiol (CBD) is a biologically active, non-psychotropic component of Cannabis sativa whose popularity has grown exponentially in recent years.…
Abstract Cannabis has been reported to contain over 560 different compounds, out of which 120 are cannabinoids. Among the cannabinoids,…
Abstract Purpose: Δ9-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ9-tetrahydrocannabinol, synthesized with the aim of improving the ocular bioavailability of the parent…
Abstract The goal of this study was to investigate the potential for a cannabidiol-rich cannabis extract (CRCE) to interact with…
Abstract The goal of this study was to investigate Cannabidiol (CBD) hepatotoxicity in 8-week-old male B6C3F1 mice. Animals were gavaged…
Abstract Purpose: The aim of the present study was to evaluate the utility of the relatively hydrophilic Δ9-tetrahydrocannabinol (THC) prodrugs,…