Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats
Abstract Neonatal hypoxia-ischemia (HI) is a risk factor for myelination disturbances, a key factor for cerebral palsy. Cannabidiol (CBD) protects…
M. Ruth Pazos
Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer’s disease
Abstract Background: Because of their low levels of expression and the inadequacy of current research tools, CB2 cannabinoid receptors (CB2R)…
Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson’s disease: possible involvement of different binding sites at the PPARγ receptor
Abstract Background: Neuroprotection with cannabinoids in Parkinson’s disease (PD) has been afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the…
The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways
Abstract Scleroderma is a group of rare diseases associated with early and transient inflammation and vascular injury, followed by fibrosis…