Long-range conformational changes in the nucleotide-bound states of the DEAD-box helicase Vasa
Abstract DEAD-box helicases use ATP to unwind short double-stranded RNA (dsRNA). The helicase core consists of two discrete domains, termed…
Luca Codutti
Histone chaperone exploits intrinsic disorder to switch acetylation specificity
Abstract Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones…