Case report: High-grade serous tubo-ovarian carcinoma with FGFR2::IQCG fusion and insights into targetability
Abstract FGFR2 fusion is one of the classes of emerging therapeutic targets of precision oncology and is observed in many…
Liying Zhang
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function
Abstract TRPV2 is a ligand-operated temperature sensor with poorly defined pharmacology. Here, we combine calcium imaging and patch-clamp electrophysiology with…
Psychosocial and behavioral factors affecting inflammation among pregnant African American women☆
Abstract African American women are reported to have greater inflammation compared with women from other racial groups. Higher inflammation during…
The role of Mediator and Little Elongation Complex in transcription termination
Abstract Mediator is a coregulatory complex that regulates transcription of Pol II-dependent genes. Previously, we showed that human Mediator subunit…