Order and disorder—An integrative structure of the full-length human growth hormone receptor
Abstract Integrative structure of a complete cytokine receptor in a nanodisc opens for mechanistic decoding of disorder-based biology. Authors: Noah…
Lise Arleth
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
Abstract Dynamic interactions of proteins with lipid membranes are essential regulatory events in biology, but remain rudimentarily understood and particularly…
Orchestration of signaling by structural disorder in class 1 cytokine receptors
Abstract Background: Class 1 cytokine receptors (C1CRs) are single-pass transmembrane proteins responsible for transmitting signals between the outside and the…