Abstract Background: Fundamental gaps in knowledge exist in understanding the tissue distribution of cannabinoids, cannabidiol (CBD) and tetrahydrocannabinol (THC), following…
Abstract Currently, peripheral tissue distribution of cannabinoids after treatment is poorly understood. This pilot study sought to examine the early…
Abstract Using the rat conditioned gaping model of nausea, the interoceptive insular cortex (IIC) has been identified as a critical…
Abstract Despite the advent of classic anti-emetics, chemotherapy-induced nausea is still problematic, with vomiting being somewhat better managed in the…
Abstract Over the years, animal studies have revealed a role for the endocannabinoid system in the regulation of multiple aspects…
Abstract Chemotherapy-induced nausea is one of the most distressing symptoms reported by patients undergoing treatment, and even with the introduction…