The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
Abstract Tau accumulation is a major pathological hallmark of Alzheimer’s disease (AD) and other tauopathies, but the mechanism(s) of tau…
Leonard Petrucelli
Tau exhibits unique seeding properties in globular glial tauopathy
Abstract Electronic supplementary material: The online version of this article (10.1186/s40478-019-0691-9) contains supplementary material, which is available to authorized users.…
Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant
Abstract Electronic supplementary material: The online version of this article (10.1186/s40478-019-0661-2) contains supplementary material, which is available to authorized users.…