Leland J. Dunwoodie

May 25, 2018

Sorting Five Human Tumor Types Reveals Specific Biomarkers and Background Classification Genes

Abstract We applied two state-of-the-art, knowledge independent data-mining methods – Dynamic Quantum Clustering (DQC) and t-Distributed Stochastic Neighbor Embedding (t-SNE)…

January 13, 2018

Discovery and validation of a glioblastoma co-expressed gene module

Abstract Tumors exhibit complex patterns of aberrant gene expression. Using a knowledge-independent, noise-reducing gene co-expression network construction software called KINC,…

August 17, 2017

Discovering Condition-Specific Gene Co-Expression Patterns Using Gaussian Mixture Models: A Cancer Case Study

Abstract A gene co-expression network (GCN) describes associations between genes and points to genetic coordination of biochemical pathways. However, genetic…