Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis
Abstract Endocannabinoid (eCB) signaling is markedly decreased in the hippocampus (Hip) of aged mice, and the genetic deletion of the…
Laura Bindila
Behavioral Studies of p62 KO Animals with Implications of a Modulated Function of the Endocannabinoid System
Abstract Elementary emotional states and memory can be regulated by the homeostasis of the endocannabinoid system (ECS). Links between the…
Fear extinction learning and anandamide: an fMRI study in healthy humans
Abstract Anxiety- and trauma-related disorders are severe illnesses with high prevalence. Current treatment options leave room for improvement and the…
The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders
Abstract Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line…
Cerebrospinal fluid endocannabinoid levels in Gilles de la Tourette syndrome
Abstract Gilles de la Tourette syndrome (TS) is a complex neurodevelopmental disorder characterized by the presence of motor and vocal…