Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Abstract Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles…
Konnor La
Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas
Abstract Precision oncology uses genomic evidence to match patients with treatment but often fails to identify all patients who may…
Mitochondrial respiratory gene expression is suppressed in many cancers
Abstract The fundamental metabolic decision of a cell, the balance between respiration and fermentation, rests in part on expression of…