Modulating FOXO3 transcriptional activity by small, DBD-binding molecules
Abstract FOXO transcription factors are critical regulators of cell homeostasis and steer cell death, differentiation and longevity in mammalian cells.…
Klara Kohoutova
Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics
Abstract FOXO transcription factors regulate cellular homeostasis, longevity and response to stress. FOXO1 (also known as FKHR) is a key…