Abstract Cannabidiol (CBD) is a non-psychoactive component of cannabis that has been studied as a potential therapy for chronic pain.…
Abstract Recreational use of synthetic cannabinoid agonists (i.e., “spice compounds”) that target the cannabinoid type 1 receptor (CB1) can cause…
Abstract Δ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors…
Abstract Background: Adolescent cannabinoid exposure can have long-lasting effects on the brain, particularly in the prefrontal cortex, where the reelin…
Abstract The Cannabis sativa plant has been used for centuries as a recreational drug and more recently in the treatment…
Abstract While the opioid crisis has justifiably occupied news headlines, emergency rooms are seeing many thousands of visits for another…
Abstract In the central nervous system (CNS), cannabinoid receptor 1 (CB1R) is preferentially expressed in axons where it has a…
Abstract Cannabis use has become popular among athletes, many of whom are exposed to repetitive subconcussive head impacts. We aimed…
Abstract In addition to phytocannabinoids, cannabis contains terpenoids that are claimed to have a myriad of effects on the body.…
Abstract Long-term cannabis use during adolescence has deleterious effects in brain that are largely ascribed to the activation of cannabinoid-1…