Ke Ding

June 12, 2025

Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma

Abstract Using novel mouse models, we establish cyclin-dependent kinase 12 (CDK12) as a bona fide tumor suppressor gene in tubo-ovarian…

August 23, 2022

A score of DNA damage repair pathway with the predictive ability for chemotherapy and immunotherapy is strongly associated with immune signaling pathway in pan-cancer

Abstract DNA damage repair (DDR) is critical in maintaining normal cellular function and genome integrity and is associated with cancer…

November 23, 2021

Analysis of the Expression and Prognostic Value of MSH2 in Pan-Cancer Based on Bioinformatics

Abstract Background: MutS homolog 2 (MSH2), with the function of identifying mismatches and participating in DNA repair, is the “housekeeping…

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