Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Abstract Background and Objective: Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B…
Katiuscia Martinello
Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1
Abstract Objective: Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions…
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis
Abstract We compared GABAergic function and neuronal excitability in the hippocampal tissue of seven sporadic MTLE patients with a patient…