Julia Krushkal

June 28, 2025

Prevalence and impact of molecular variation in the three-prime repair exonuclease 1 TREX1 and its implications for oncology

Abstract Background: The three-prime repair exonuclease 1, TREX1, degrades cytosolic DNA to prevent aberrant immune activation. Its inactivation results in…

April 11, 2018

Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment

Abstract Background: The APOBEC gene family of cytidine deaminases plays important roles in DNA repair and mRNA editing. In many…