Minor Cannabinoids CBD, CBG, CBN and CBC differentially modulate sensory neuron activation
Abstract The use of minor cannabinoids has been advanced, in part, by the idea of providing relief from pain and…
Judith Hellman
Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons
Abstract Interest in nonpsychotropic cannabinoids like cannabinol (CBN) is increasing for pain therapy. This study delivers critical insights into CBN’s…
Elucidating the Mechanism of Metabolism of Cannabichromene by Human Cytochrome P450s
Abstract Cannabichromene (CBC) is a nonpsychoactive phytocannabinoid well-known for its wide-ranging health advantages. However, there is limited knowledge regarding its…
N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes
Abstract Background: The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain…