John Hardy

June 17, 2024

Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia

Abstract Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the…

January 16, 2020

Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates

Abstract Corticobasal degeneration typically progresses gradually over 5–7 years from onset till death. Fulminant corticobasal degeneration cases with a rapidly…

January 9, 2018

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

Abstract Background: Converging evidence suggests that immune-mediated dysfunction plays an important role in the pathogenesis of frontotemporal dementia (FTD). Although…