Metabolomic profiling of cannabis use and cannabis intoxication in humans
Abstract Acute intoxication from Δ9-tetrahydrocannabinol (THC, the primary active ingredient of cannabis) can lead to neurocognitive impairment and interference with…
Johannes G. Ramaekers
Cannabis Use and Neuroadaptation: A Call for Δ9-Tetrahydrocannabinol Challenge Studies
Abstract Currently, the assessment of the neurobehavioral consequences of repeated cannabis use is restricted to studies in which brain function…
Sex differences in acute cannabis effects revisited: Results from two randomized, controlled trials
Abstract Some evidence suggests that males and females may differ in their responses to acute cannabis effects, including subjective drug…
Psychotomimetic symptoms after a moderate dose of a synthetic cannabinoid (JWH-018): implications for psychosis
Abstract Background: Synthetic cannabinoids (SCs) are the largest class of novel psychoactive substances (NPS) and are associated with an increased…
Cannabis increases susceptibility to false memory
Abstract This unique randomized, double-blind, placebo-controlled trial examined the susceptibility to false memories under the influence of cannabis, using a…
Reduced responsiveness of the reward system is associated with tolerance to cannabis impairment in chronic users
Abstract Cannabis is the most commonly used illicit drug in the world. However, because of a changing legal landscape and…
Detection of Δ9 THC in oral fluid following vaporized cannabis with varied cannabidiol (CBD) content: An evaluation of two point‐of‐collection testing devices
Abstract Point‐of‐collection testing (POCT) for Δ9‐tetrahydrocannabinol (THC) in oral fluid is increasingly used to detect driving under the influence of…
False memory formation in cannabis users: a field study
Abstract Rationale: Cannabis use is widespread and has previously been associated with memory impairments. However, the role of cannabis in…
Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition
Abstract Background: The main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), can impair driving performance. Cannabidiol (CBD), a non-intoxicating cannabis component,…
Psychopathological symptoms associated with synthetic cannabinoid use: a comparison with natural cannabis
Abstract Background: Synthetic cannabinoids (SCs) are a class of new psychoactive substances that have been rapidly evolving around the world…