FHL2 facilitates LUSC growth and therapy resistance through PI3K/AKT/mTOR activation
Abstract Four and a half LIM domain protein 2 (FHL2) plays a key role in tumorigenesis and progression. This study…
Jing Wang
Comprehensive Cellular Senescence Evaluation to Aid Targeted Therapies
Abstract Drug resistance to a single agent is common in cancer-targeted therapies, and rational drug combinations are a promising approach…
Role of LMO7 in cancer (Review)
Abstract Cancer constitutes a multifaceted ailment characterized by the dysregulation of numerous genes and pathways. Among these, LIM domain only…
Undifferentiated high-grade pleomorphic sarcoma of the common bile duct: A case report and review of literature
Abstract BACKGROUND: Undifferentiated pleomorphic sarcoma (UPS) is a rare malignant mesenchymal tumor with a poor prognosis. It mainly occurs in…
Identification of key genes and their correlation with immune infiltration in osteoarthritis using integrative bioinformatics approaches and machine-learning strategies
Abstract Osteoarthritis (OA) is a common degenerative joint disease and is closely associated with chronic, low-grade inflammation. Regulating ferroptosis by…
Genomic, epigenomic, and transcriptomic signatures for telomerase complex components: a pan‐cancer analysis
Abstract Telomerase activation is required for malignant transformation. Recent advances in high‐throughput technologies have enabled the generation of complex datasets,…
Dietary supplementation of hemp oil in teddy dogs: Effect on apparent nutrient digestibility, blood biochemistry and metabolomics
Abstract Present study aimed to evaluate the influence of distinct concentration of dietary supplements hemp oil on apparent nutrient digestibility,…
Cannabinoid Receptors in Myocardial Injury: A Brother Born to Rival
Abstract Cannabinoid receptors typically include type 1 (CB1) and type 2 (CB2), and they have attracted extensive attention in the…
Prioritizing Cancer Genes Based on an Improved Random Walk Method
Abstract Identifying driver genes that contribute to cancer progression from numerous passenger genes, although a central goal, is a major…
Comprehensive Analysis of the Expressionand Prognosis for TDO2 in Breast Cancer
Abstract A plethora of previous studies have been focused on the role of indoleamine 2,3-dioxygenase 1 (IDO1) in cancer immunity;…