Jaroslav Blahos

April 22, 2024

Hexahydrocannabinol (HHC) and Δ9-tetrahydrocannabinol (Δ9-THC) driven activation of cannabinoid receptor 1 results in biased intracellular signaling

Abstract The Cannabis sativa plant has been used for centuries as a recreational drug and more recently in the treatment…

July 20, 2023

SGIP1 in axons prevents internalization of desensitized CB1R and modifies its function

Abstract In the central nervous system (CNS), cannabinoid receptor 1 (CB1R) is preferentially expressed in axons where it has a…

February 27, 2021

SGIP1 is involved in regulation of emotionality, mood, and nociception and modulates in vivo signalling of cannabinoid CB1 receptors

Abstract Background and Purpose: Src homology 3‐domain growth factor receptor‐bound 2‐like endophilin interacting protein 1 (SGIP1) interacts with cannabinoid CB1…