A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand-binding assay
Abstract Introduction: The kinetics of ligand binding to G protein-coupled receptors (GPCRs) is an important optimization parameter in drug discovery.…
Jara Bouma
Structural basis of selective cannabinoid CB2 receptor activation
Abstract Cannabinoid CB2 receptor (CB2R) agonists are investigated as therapeutic agents in the clinic. However, their molecular mode-of-action is not…