Abstract Synthetic cannabinoids have exhibited unpredictable abuse liabilities, especially self-administration (SA) responses in normal rodent models, despite seemingly inducing addiction-like…
Abstract Interaction of cannabinoid receptor type 1 (CB1) and GABAergic neuronal activity is involved in drug abuse-related behavior. However, its…
Abstract A major predictor of the efficacy of natural or synthetic cannabinoids is their binding affinity to the cannabinoid type…
Abstract Synthetic cannabinoids are one of most abused new psychoactive substances. The recreational use of abused drug has aroused serious…
Abstract Synthetic cannabinoids (CBs) such as the JWH series have caused social problems concerning their abuse liability. Because the JWH…