A Comprehensive Analysis of the Role of DSN1 in Pan-Cancer Prognosis and Immunotherapy
Abstract Background: Dosage Suppressor of NNF1 (DSN1) is a component of the MIS12 kinetochore complex crucial in the cell cycle…
Hongyue Zhang
Targeting PCSK9 to upregulate MHC-II on the surface of tumor cells in tumor immunotherapy
Abstract Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9), the last member of the proprotein convertase family, functions as a classic…
Age and BRAFV600E Mutation Stratified Patients with Cytologically Benign Thyroid Nodules
Abstract Purpose: Our objective was to evaluate the diagnostic performance of BRAFV600E mutation for malignant, and to identify clinical characteristics…
Comprehensive pan-cancer analysis of expression profiles and prognostic significance for NUMB and NUMBL in human tumors
Abstract NUMB has been initially identified as a critical cell fate determinant that modulates cell differentiation via asymmetrical partitioning during…
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma
Abstract Human osteosarcoma is considered a malignant tumor with poor prognosis that readily metastasizes. Tetrahydrocurcumin (THC) has been reported to…