A Novel Strategy to Identify Prognosis-Relevant Gene Sets in Cancers
Abstract Molecular prognosis markers hold promise for improved prediction of patient survival, and a pathway or gene set may add…
Hongyan Guo
Comprehensive Analysis of Co-Mutations Identifies Cooperating Mechanisms of Tumorigenesis
Abstract Simple Summary: Somatic mutations are one of the most important causal factors of cancers. In this study, we show…
Conditional transcriptional relationships may serve as cancer prognostic markers
Abstract Background: While most differential coexpression (DC) methods are bound to quantify a single correlation value for a gene pair…
Comprehensive landscape of the renin-angiotensin system in Pan-cancer: a potential downstream mediated mechanism of SARS-CoV-2
Abstract Background: SARS-CoV-2, the cause of the worldwide COVID-19 pandemic, utilizes the mechanism of binding to ACE2 (a crucial component…
Architectures and accuracy of artificial neural network for disease classification from omics data
Abstract Background: Deep learning has made tremendous successes in numerous artificial intelligence applications and is unsurprisingly penetrating into various biomedical…
Latitudinal Adaptation and Genetic Insights Into the Origins of Cannabis sativa L.
Abstract Cannabis is one of the most important industrial crops distributed worldwide. However, the phylogeographic structure and domestication knowledge of…