Hirohisa Watanabe

March 5, 2025

Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypes

Abstract Tau, a microtubule-binding protein linked to tauopathies like Alzheimer’s disease and frontotemporal lobar degeneration (FTLD), has 3-repeat (3R) and…

July 22, 2024

Conventional magnetic resonance imaging key features for distinguishing pathologically confirmed corticobasal degeneration from its mimics: a retrospective analysis of the J-VAC study

Abstract Purpose: Due to the indistinguishable clinical features of corticobasal syndrome (CBS), the antemortem differentiation between corticobasal degeneration (CBD) and…