Validation of transcriptome signature reversion for drug repurposing in oncology
Abstract Transcriptome signature reversion (TSR) has been extensively proposed and used to discover new indications for existing drugs (i.e. drug…
Henk-Jan Guchelaar
Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics
Abstract Objective Nausea and vomiting are the most distressful side effects of cytotoxic drugs in cancer patients. Antiemetics are commonly…