Renal Protection of HWL‐088and ZLY‐032, Two Dual GPR40/PPARδ Agonists, in Adenine‐Induced Renal Fibrosis Model
Abstract This research examined the potential of novel GPR40/PPARδ dual agonists, HWL‐088 and ZLY‐032, to protect the kidneys in a…
Haoying Yang
E3 ubiquitin ligase MAGI3 degrades c-Myc and acts as a predictor for chemotherapy response in colorectal cancer
Abstract Background: Recurrence and chemoresistance constitute the leading cause of death in colorectal cancer (CRC). Thus, it is of great…
The Phytochemical Potential for Brain Disease Therapy and the Possible Nanodelivery Solutions for Brain Access
Abstract Plant-derived phytochemicals have gifted humans with vast therapeutic potentials. Yet, the unique features of the blood–brain barrier significantly limit…
The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division
Abstract During the asymmetric division of Drosophila neuroblasts (NBs), the scaffold Miranda (Mira) coordinates the subcellular distribution of cell-fate determinants…