The unfolded protein response links tumor aneuploidy to local immune dysregulation
Abstract Aneuploidy is a chromosomal abnormality associated with poor prognosis in many cancer types. Here, we tested the hypothesis that…
Hannah Carter
GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors
Abstract G protein-coupled receptors (GPCRs) are the most widely targeted gene family for Food and Drug Administration (FDA)-approved drugs. To…