Brain CB2 receptor: a new target in medication development for treating opioid use disorder in rodents
Abstract Opioid use disorder (OUD) remains a major public health crisis, underscoring the urgent need for safer and more effective…
Hannah Alton
Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout mice
Abstract Co-administration of cannabinoids and opioids has been shown to enhance analgesic effects. However, the underlying mechanisms remain unclear. One…
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice
Abstract G protein-coupled receptor 55 (GPR55) has been thought to be a putative cannabinoid receptor. However, little is known about…
GPR55 is expressed in glutamate neurons and functionally modulates nicotine taking and seeking in rats and mice
Abstract Cannabis legalization continues to progress in the USA for medical and recreational purposes. G protein-coupled receptor 55 (GPR55) is…
PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice
Abstract Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that regulate gene expression. Δ9-tetrahydrocannabinol (Δ9-THC) is a PPARγ…
PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice
Abstract Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that regulate gene expression. Δ9-tetrahydrocannabinol (Δ9-THC) is a PPARg…