Multi-dimensional analysis reveals the potential of PDK4 as a tumor biomarker and target for immunotherapy
Abstract Purpose: To explore the clinical significance of pyruvate dehydrogenase kinase 4 (PDK4) in pan-cancer and its potential as a…
Abstract Purpose: To explore the clinical significance of pyruvate dehydrogenase kinase 4 (PDK4) in pan-cancer and its potential as a…
Abstract Background: Congenital biliary dilatation (CBD) represents a prevalent congenital anomaly in pediatric surgery, with concurrent choledocholithiasis observed in a…
Abstract Orthotropic Steel Bridge Decks (OSBDs) are often used in long-span bridges due to their high performance and ease of…
Abstract The intricacies of tumour microenvironment, particularly the extracellular matrix (ECM), underscore its pivotal function in modulating tumour progression and…
Abstract Background: Tumor mRNA vaccines have been identified as a promising technology for cancer therapy in multiple cancer types, while…
Abstract Cannabidiol (CBD), derived from the plant cannabis, can be used in the cosmetics industry for its antioxidant, anti-inflammatory, anti-wrinkle…
Abstract Background: Huang Lian (HL), one of the traditional Chinese medicines (TCMs) that contains multiple active components including berberine (BBR),…
Abstract Background: The APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) family-mediated mutagenesis is widespread in human cancers. However, our…
Abstract Background: Runt-related transcription factor 1 (RUNX1) is a vital regulator of mammalian expression. Despite multiple pieces of evidence indicating…
Abstract Some previous studies have shown that PLOD2 has some value in tumorigenesis. However, the broad significance of PLOD2 has…