Abstract Background: Preclinical and human data suggest that psychosis onset involves hippocampal glutamatergic dysfunction, driving hyperactivity and hyperperfusion in a…
Abstract High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally,…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-021-01318-z. Article type: Research Article Keywords: Clinical high risk,…
Abstract Background: Emerging evidence supports the antipsychotic effect of cannabidiol, a non-intoxicating component of cannabis, in people with psychosis. Preclinical…
Abstract Emotional dysregulation and anxiety are common in people at clinical high risk for psychosis (CHR) and are associated with…
Abstract Cannabis use during the critical neurodevelopmental period of adolescence, may lead to brain structural, functional, and histological alterations that…
Abstract Cannabis has been associated with deficits in memory performance. However, the neural correlates that may underpin impairments remain unclear.…
Abstract Rationale: Prolonged use of cannabis, the most widely used illicit drug worldwide, has been consistently associated with impairment in…
Abstract Adolescent abstinent cannabis users showed significantly greater activation in the dorsolateral and ventrolateral prefrontal and posterior parietal cortices compared…