Tau seeding activity in skin biopsy differentiates tauopathies from synucleinopathies
Abstract Most neurodegenerative diseases lack definitive diagnostic tests, and the identification of easily accessible and reliable biomarkers remains a critical…
Giuseppe Legname
Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease
Abstract Chronic wasting disease (CWD) is a highly infectious prion disease of cervids. Accumulation of prions, the disease-specific structural conformers…
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy
Abstract Background: Parkinson’s disease (PD) is a neurodegenerative disorder whose diagnosis is often challenging because symptoms may overlap with neurodegenerative…