Pregnenolone blocks cannabinoid-induced acute psychotic-like states in mice
Abstract Cannabis-induced acute psychotic-like states (CIAPS) represent a growing health issue, but their underlying neurobiological mechanisms are poorly understood. The…
Giovanni Marsicano
Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration
Abstract The cannabinoid type 1 (CB1) receptor is widely distributed in the brain and peripheral organs where it regulates cellular…
Cannabinoid receptor type-1: breaking the dogmas
Abstract The endocannabinoid system (ECS) is abundantly expressed in the brain. This system regulates a plethora of physiological functions and…
Genetic Dissection of Behavioural and Autonomic Effects of Δ9-Tetrahydrocannabinol in Mice
Abstract Marijuana and its main psychotropic ingredient Δ9-tetrahydrocannabinol (THC) exert a plethora of psychoactive effects through the activation of the…