Structure and dynamics of the quaternary hunchback mRNA translation repression complex
Abstract A key regulatory process during Drosophila development is the localized suppression of the hunchback mRNA translation at the posterior,…
Frank Gabel
Histone chaperone exploits intrinsic disorder to switch acetylation specificity
Abstract Histones, the principal protein components of chromatin, contain long disordered sequences, which are extensively post-translationally modified. Although histone chaperones…
Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
Abstract Post-transcriptional mechanisms play a predominant role in the control of microRNA (miRNA) production. Recognition of the terminal loop of…