Microglial Cells as a Link between Cannabinoids and the Immune Hypothesis of Psychiatric Disorders
Abstract Psychiatric disorders are one of the leading causes of disability worldwide. Although several therapeutic options are available, the exact…
Francisco S. Guimarães
Cannabidiol Attenuates Sensorimotor Gating Disruption and Molecular Changes Induced by Chronic Antagonism of NMDA receptors in Mice
Abstract Background: Preclinical and clinical data suggest that cannabidiol (CBD), a major non-psychotomimetic compound from Cannabis sativa, induces antipsychotic-like effects.…
Effects of Pubertal Cannabinoid Administration on Attentional Set-Shifting and Dopaminergic Hyper-Responsivity in a Developmental Disruption Model of Schizophrenia
Abstract Background: Adolescent exposure to cannabinoids in vulnerable individuals is proposed to be a risk factor for psychiatric conditions later…
Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration
Abstract Disc degeneration is a multifactorial process that involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan…