Francesca Felicia Operto

June 21, 2025

Is highly purified cannabidiol a treatment opportunity for drug‐resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?

Abstract Objective: This study aimed to evaluate the efficacy and safety of adjunctive, highly purified Cannabidiol (Epidiolex®) in individuals with…

August 29, 2024

Opioid and Cannabinoid Systems in Pain: Emerging Molecular Mechanisms and Use in Clinical Practice, Health, and Fitness

Abstract Pain is an unpleasant sensory and emotional experience. Adequate pain control is often challenging, particularly in patients with chronic…

June 14, 2024

CDKL5 deficiency-related neurodevelopmental disorders: a multi-center cohort study in Italy

Abstract CDKL5 deficiency disorder (CDD) is a complex clinical condition resulting from non-functional or absent CDKL5 protein, a serine–threonine kinase…