ALKBH5, an m6A demethylase, attenuates tumor growth and inhibits metastasis in papillary thyroid carcinoma
Abstract The significance of ALKBH5 in erasing mRNA methylation in mRNA biogenesis, decay, and translation control has emerged as a…
Fengxin Huang
CDCM: a correlation-dependent connectivity map approach to rapidly screen drugs during outbreaks of infectious diseases
Abstract In the context of the global damage caused by coronavirus disease 2019 (COVID-19) and the emergence of the monkeypox…
Prediction of multiple types of drug interactions based on multi-scale fusion and dual-view fusion
Abstract Potential drug-drug interactions (DDI) can lead to adverse drug reactions (ADR), and DDI prediction can help pharmacy researchers detect…
Genetically predicted vitamin C levels significantly affect patient survival and immunotypes in multiple cancer types
Abstract Background: Recent observational studies and meta-analyses have shown that vitamin C reduces cancer incidence and mortality, but the underlying…
Pan-cancer analysis of DEPDC1 as a candidate prognostic biomarker and associated with immune infiltration
Abstract Background: DEP domain containing 1 (DEPDC1) gene is upregulated in several malignancies and contributes to tumorigenesis. Although the role…
CMTCN: a web tool for investigating cancer-specific microRNA and transcription factor co-regulatory networks
Abstract Transcription factors (TFs) and microRNAs (miRNAs) are well-characterized trans-acting essential players in gene expression regulation. Growing evidence indicates that…