Feng Ni

August 25, 2023

Unique epitope–antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surface display

Abstract Carbonic anhydrase (CA)-IX is an extracellular enzyme that is essential in the adaptation of tumor cells to their increasingly…

February 19, 2021

Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor

Abstract Ligand-activated signaling through the type 1 insulin-like growth factor receptor (IGF1R) is implicated in many physiological processes ranging from…

February 21, 2019

Identification and characterization of a factor Va-binding site on human prothrombin fragment 2

Abstract The fragment 2 domain (F2) of prothrombin and its interaction with factor (F) Va is known to contribute significantly…