Reactivation of Multiple Fetal miRNAs in Lung Adenocarcinoma
Abstract Simple Summary: Patterns of microRNA expression in fetal tissues are not well-characterized, due to the rarity of human fetal…
Emily A. Vucic
Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression…
Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer
Abstract The NFE2-related factor 2 (NRF2) pathway is critical to initiate responses to oxidative stress; however, constitutive activation occurs in…