Oxidative Stress and Its Consequences in the Blood of Rats Irradiated with UV: Protective Effect of Cannabidiol
Abstract UVA/UVB radiation disturbs the redox balance of skin cells, and metabolic consequences can be transferred into the blood and…
Elżbieta Skrzydlewska
Protective Effects of Cannabidiol on the Membrane Proteome of UVB-Irradiated Keratinocytes
Abstract Ultraviolet (UV) radiation contained in sunlight disturbs the redox state of skin cells, leading to changes in the structures…
The Effect of Cannabidiol on UV-Induced Changes in Intracellular Signaling of 3D-Cultured Skin Keratinocytes
Abstract Human epidermal keratinocytes are constantly exposed to UV radiation. As a result, there is a significant need for safe…
Oxidative Stress and Lipid Mediators Modulate Immune Cell Functions in Autoimmune Diseases
Abstract Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and rheumatic arthritis (RA), are caused by a combination of environmental…
Changes in Lipid Profile of Keratinocytes from Rat Skin Exposed to Chronic UVA or UVB Radiation and Topical Application of Cannabidiol
Abstract UV radiation is a well-established environmental risk factor known to cause oxidative stress and disrupt the metabolism of keratinocyte…
Cannabidiol Modifies the Formation of NETs in Neutrophils of Psoriatic Patients
Abstract Psoriasis is associated with increased production of reactive oxygen species which leads to oxidative stress. As antioxidants can provide…
Cannabidiol-Mediated Changes to the Phospholipid Profile of UVB-Irradiated Keratinocytes from Psoriatic Patients
Abstract UVB phototherapy is treatment for psoriasis, which increases phospholipid oxidative modifications in the cell membrane of the skin. Therefore,…
Involvement of Metabolic Lipid Mediators in the Regulation of Apoptosis
Abstract Apoptosis is the physiological mechanism of cell death and can be modulated by endogenous and exogenous factors, including stress…
Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris
Abstract Psoriasis is a chronic inflammatory skin disease characterized by dysregulated keratinocyte differentiation, but oxidative stress also plays an important…
Antioxidative and Anti-Inflammatory Properties of Cannabidiol
Abstract Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of Cannabis sativa L. CBD is non-psychoactive but exerts…