Epileptogenesis in tuberous sclerosis complex-related developmental and epileptic encephalopathy
Abstract Epileptogenesis in infants with tuberous sclerosis complex (TSC) is a gradual and dynamic process, leading to early onset and…
Eleonora Aronica
GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol
Abstract Recently, the potential use of phytocannabinoids (pCBs) to treat different pathological conditions has attracted great attention in the scientific…
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis
Abstract We compared GABAergic function and neuronal excitability in the hippocampal tissue of seven sporadic MTLE patients with a patient…
Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission?
Abstract γ-Aminobutyric acid type A receptors (GABAARs) are the main inhibitory mediators in the central nervous system (CNS). GABAARs are…
Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin
Abstract Cannabidivarin (CBDV) and cannabidiol (CBD) have recently emerged among cannabinoids for their potential antiepileptic properties, as shown in several…