Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates
Abstract Transactive response DNA-binding Protein of 43 kDa (TDP-43) assembles various aggregate forms, including biomolecular condensates or functional and pathological…
Douglas V. Laurents
NMR Characterization of Angiogenin Variants and tRNAAla Products Impacting Aberrant Protein Oligomerization
Abstract Protein oligomerization is key to countless physiological processes, but also to abnormal amyloid conformations implicated in over 25 mortal…