Dinahlee Saturnino Guarino

June 9, 2025

Development and In Vitro Characterization of [3H]GMC-058 as Radioligand for Imaging Parkinsonian-Related Proteinopathies

Abstract The molecular imaging of α-synuclein (α-syn) pathology in Parkinson’s disease (PD) and related movement disorders is a clinically unmet…

March 11, 2025

Structure–Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers

Abstract Structure–activity relationship studies were performed on a library of synthesized compounds based on previously identified tau ligands. The top…

November 11, 2024

Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET Radioligand

Abstract The accumulation of aggregated α-synuclein (α-syn) is a pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. Here within,…