Absence of an embryonic stem cell DNA methylation signature in human cancer
Abstract Background: Differentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory…
Devin C. Koestler
Integrative epigenetic and genetic pan-cancer somatic alteration portraits
Abstract Genetic and epigenetic alterations are required for carcinogenesis and the mutation burden across tumor types has been investigated. Here,…